The struggle for gut supremacy

Have you ever wondered why probiotics and microbiota are natural allies for gut health?

In our ongoing journey towards understanding and optimizing our health, one area that continues to garner significant attention is the intricate ecosystem within our gut-intestinal tract. Emerging research highlighting the central role of probiotics in promoting gut health. Let’s explore this special relationship!

The Importance of Gut Microbiota Equilibrium

Within the human gut resides a vast ecosystem of trillions of microorganisms, collectively known as the gut microbiota. Its balanced dynamic composition intricately shapes our gastrointestinal physiology and it is indispensable for nutrient absorption, essential compounds production, bile recycling, and immune modulation. However, modern habits, including use of antibiotics, dietary changes, and stress, can disrupt the structure and functionality of the gut microbiota, leading to   dysbiosis, and development of many intestinal disorders.

How Probiotics Work in the Gut

Probiotics are one of the key solutions to restore intestinal eubiosis. Upon ingestion, probiotics transit through the gastrointestinal tract, reaching the colon where they exert their effects:

Competing for the territory. One key mechanism through which probiotics exert their beneficial effects is competitive exclusion. By competing with pathogenic microorganisms for nutrients and adhesion sites along the intestinal epithelium, probiotics prevent the colonization and proliferation of harmful bacteria.

Supporting the team. Probiotics produce various natural antimicrobial substances, such bacteriocins, and lactic acid which create an unfavorable environment for pathogenic bacteria, while supporting the growth and survival of beneficial microbes within the gut ecosystem. Moreover, probiotic’s byproducts, named postbiotics, nourish the cells lining the gut.

Strengthening the barrier. Additionally, probiotics can enhance the integrity of the intestinal barrier by stimulating the production of mucin and by upregulating the expression of tight junction proteins, which maintain the structural integrity of the intestinal epithelium. Thus, probiotics prevent the translocation of harmful bacteria across the gut mucosa.

Training immunity. Probiotics and their derivatives, such as cell wall components and metabolites, interact with the host’s immune system. They modulate immune responses within the gut mucosa, stimulating immune cells to produce anti-inflammatory cytokines.

In conclusion. Probiotics play a crucial role in supporting gut health by modulating the composition and function of the gut microbiota. These beneficial bacteria help maintain a diverse and resilient microbiota, which is essential for the improvement of gastrointestinal function and the overall well-being.

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    Marta Lo Re


    R&D Assistant

    Latest Probiotic's Guide