Microencapsulation of new probiotic formulations for gastrointestinal delivery: in vitro study to assess viability and biological properties

The effects of microencapsulation on the viability of the strains in conditions simulating the gastrointestinal tract and under industrial processes conditions

Probiotics are defined as live microorganisms, which, when administered in sufficient amount, confer beneficial effects to the host including maintenance of health-promoting gut microflora, inhibition of pathogens’ growth and stimulation of the immune system (Adhikari et al. 2000; WHO 2001; Robles Alonso and Guarner 2013). Probiotics are highly stable in dairy products when compared to non-dairy products, depending on the selection of the durable strains in harsh environmental conditions and on the prebiotics used (Topping et al. 2003). The majority of probiotic bacteria do not have the capacity to survive under the adverse conditions such as the strong acidity and the presence of bile salts in the gastrointestinal tract (GI)…

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